Wavelength-dependent penetration depths of ultraviolet radiation in human skin
Wavelength-dependent penetration depths of ultraviolet radiation in human skin
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DOI：
10.1117/1.2957970
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发表时间：
2008-07-01
影响因子：
3.5
通讯作者：
Tronnier, Hagen
中科院分区：
文献类型：
--
作者：
Meinhardt, Merve;Krebs, Ronald;Tronnier, Hagen
紫外线在人体皮肤中的穿透深度是估计紫外线（UV）辐射可能的光生物学影响的基本参数。我们已经确定了人体皮肤在体内的吸收光谱的波长范围从290至341 nm的3 nm的步骤，使用激光光声和计算各自的渗透深度。对研究中20名受试者的不同皮肤区域和皮肤光型（光型I：n = 3; II：n = 7; III：n = 5; IV：n = 5）的数据进行分析，揭示了个体之间的较大变异性。紫外线辐射在人体皮肤中的穿透深度高度依赖于波长和皮肤面积，但没有发现对皮肤光型的显著依赖性。（C）2008年照片光学仪器工程师学会。
The wavelength-dependent penetration depth of ultraviolet radiation in human skin is a fundamental parameter for the estimation of the possible photobiological impact of ultraviolet (UV) radiation. We have determined the absorption spectra of human skin in vivo in the wavelength range from 290 to 341 nm in 3-nm steps using laser optoacoustics and calculated the respective penetration depths. Data were analyzed with respect to different skin regions and skin phototype of the 20 subjects in the study (phototype I: n = 3; II: n = 7; III: n = 5; IV: n = 5), revealing large variability between individuals. The penetration depth of UV radiation in human skin is highly dependent on wavelength and skin area, but no significant dependence on skin phototype could be found. (C) 2008 Society of Photo-Optical Instrumentation Engineers.