Oesophageal cancer studies in the Caspian Littoral of Iran: the Caspian cancer registry.

Oesophageal cancer studies in the Caspian Littoral of Iran: the Caspian cancer registry.
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DOI:
10.1038/bjc.1973.138
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发表时间:
1973-09
影响因子:
8.8
通讯作者:
Salmasizadeh, S
Salmasizadeh, S
中科院分区:
医学1区
文献类型:
--
作者:
Mahboubi, E;Kmet, J;Cook, P J;Day, N E;Ghadirian, P;Salmasizadeh, S

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描述了里海沿岸前 3 年癌症登记的结果。主要发现证实了之前的报告,即食道癌的发病率在该地区存在很大的差异。考虑了可能的偏差来源,并证明其对发生模式的影响很小。在不同地区,女性的发病率存在三十倍的差异;男性之间有十倍的差异。在该地区的东北部,这种肿瘤在女性中至少与男性一样常见,并且比世界上几乎任何地方的任何肿瘤都更常见。相比之下,在其他肿瘤中,胃癌的发病率惊人地一致。乳腺癌显示出相反斜率的发病率梯度。
The results of the first 3 years of cancer registration on the Caspian Littoral are described. The main finding, confirming previous reports, is a very large variation within the region of the incidence of oesophageal cancer. Possible sources of bias are considered and shown to contribute little to the pattern of incidence. Among women there is a thirty-fold variation in the incidence across the regions; among men a ten-fold variation. In the north-east of the region the tumour is at least as common in women as in men, and is more common than almost any tumour anywhere in the world. Among other tumours, stomach cancer has a strikingly uniform incidence by comparison; breast cancer shows an incidence gradient of opposite slope.