Cardiovascular risk factor control and outcomes in peripheral artery disease patients in the Reduction of Atherothrombosis for Continued Health (REACH) Registry.

Cardiovascular risk factor control and outcomes in peripheral artery disease patients in the Reduction of Atherothrombosis for Continued Health (REACH) Registry.
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DOI:
10.1016/j.atherosclerosis.2008.10.023
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发表时间:
2009-06-01
期刊:
影响因子:
5.3
通讯作者:
Hirsch, Alan T
Hirsch, Alan T
中科院分区:
医学2区
文献类型:
--
作者:
Cacoub, Patrice P;Abola, Maria Teresa B;Hirsch, Alan T

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目的:研究外周动脉疾病(PAD)与冠状动脉(CAD)或脑血管疾病(CVD)在危险因素(RF)管理上的差异,以及RF控制对主要1年心血管(CV)事件发生率的影响。方法:REACH注册中心招募了68000名年龄<gt;或=45岁已确诊的动脉粥样硬化性血栓形成患者或=3rf的动脉粥样硬化血栓患者。被评估的RF控制的预测因素包括:(1)患者的人口学特征,(2)PAD的诊断模式,(3)伴随的冠心病和/或心血管疾病。结果:与冠心病或心血管疾病(但无PAD,n=47492)患者相比,PAD(n=8322)患者的RF控制频率较低(P
OBJECTIVES: To examine differences in risk factor (RF) management between peripheral artery disease (PAD) and coronary artery (CAD) or cerebrovascular disease (CVD), as well as the impact of RF control on major 1-year cardiovascular (CV) event rates.METHODS: The REACH Registry recruited >68000 outpatients aged >or=45 years with established atherothrombotic disease or >or=3 RFs for atherothrombosis. The predictors of RF control that were evaluated included: (1) patient demographics, (2) mode of PAD diagnosis, and (3) concomitant CAD and/or CVD.RESULTS: RF control was less frequent in patients with PAD (n=8322), compared with those with CAD or CVD (but no PAD, n=47492) [blood pressure; glycemia; total cholesterol; smoking cessation (each P