USES OF THE FRIES REARRANGEMENT FOR THE PREPARATION OF HYDROXYARYLKETONES. A REVIEW
USES OF THE FRIES REARRANGEMENT FOR THE PREPARATION OF HYDROXYARYLKETONES. A REVIEW
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Fries重排在制备羟基芳基酮中的用途。
DOI：
10.1080/00304949209356226
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发表时间：
1992
影响因子：
1.5
通讯作者：
Robert J. Martin
中科院分区：
文献类型：
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作者：
Robert J. Martin
羟基芳基酮具有许多工业应用。其中一些化合物具有可用于制药工业和香料工业的特性。羟基二苯甲酮通过提高其稳定性，在油漆和清漆制造、塑料、薄膜、天然或合成橡胶中找到了非常重要的应用？许多氢芳基酮及其一些衍生物用于冶金工业，用于金属的提取和分离，或者用于矿石和合金中的选择性评估。然而，羟基芳酮很重要，主要作为有机合成中的合成子。一些羟基芳酮以自然状态存在？尽管有几种反应可以制备羟基芳基酮（Friedel-Crafts 反应、Fries 重排、Hoesch 和 Nencki 反应等），但 Fries 重排通常是最合适的方法。该方法操作简单，异构体分离容易，收率好。薯条的重排也是通过光化学完成的！上一次关于 Fries 重排的调查可以追溯到 19H7，我们研究的目的是回顾该领域的最新进展。
The hydroxyarylketones have many industrial applications. Some of these compounds have properties which are useful in the pharmaceutical industry and in perfumery.'Hydroxybenzophenones find very important applications in paints and varnishes manufacturing, plastics, films, natural or synthetic rubbers by improving their stability? Many hydro~ yarylketones~ and some of their derivative~~ are used in the metallurgical industry, either for the extraction and separation of metals or for their selective estimation in ores and alloys. However, hydroxyarylketones are important, mainly as synthons in organic synthesis. Some hydroxyarylketones exist in the natural state? Although several reactions allow the preparation of hydroxyarylketones (Friedel-Crafts reaction, Fries rearrangement, Hoesch and Nencki reactions, etc.), the Fries rearrangement is usually the most suitable process. It is easy to perform, isomer separation is easy and yields are good. The Fries rearrangement has been also made by photochemistry! The last survey on Fries rearrangement dates back to 19H7 and the purpose of our study is to review recent progress in this field.