Rasmussen's encephalitis in a 58-year-old female: Still a variant?
Rasmussen's encephalitis in a 58-year-old female: Still a variant?
复制标题
DOI：
10.1017/s0317167100005175
复制
发表时间：
2006-08-01
影响因子：
3
通讯作者：
Robinson, Christopher A.
中科院分区：
文献类型：
--
作者：
Hunter, Gary R. W.;Donat, Jeffrey;Robinson, Christopher A.
背景资料：我们报告的情况下，58岁的女性与临床，放射学和组织病理学证据的拉斯穆森脑炎，代表最古老的确诊病例。病例总结：患者表现为复杂部分性癫痫发作，特征为左脸麻木和凝视。这些进展到持续性部分癫痫状态，伴随左脸抽搐，以及严重的认知障碍和所有交流的丧失。患者对静脉注射免疫球蛋白（IVIG）治疗反应良好，尽管有早期并发症，并且正在进行治疗，独立生活，认知障碍最小。结论：这是最古老的拉斯穆森脑炎确诊病例，并表明这种诊断应考虑在任何年龄的患者与适当的临床图片。我们建议IVIG作为成人拉斯穆森脑炎的一线治疗。
Background: We report the case of a 58-year-old female with clinical, radiological, and histopathological evidence of Rasmussen's encephalitis, representing the oldest confirmed case to date. Case Summary: The patient presented with complex partial seizures characterized by numbness of the left face and staring spells. These progressed to a state of epilepsia partialis continua with jerking of the left face, as well as severe cognitive impairment and loss of all communication. The patient responded well to Intravenous Immunoglobulin (IVIG) therapy despite early complications and with ongoing treatment is living independently with minimal cognitive impairment. Conclusions: This represents the oldest confirmed case of Rasmussen's encephalitis and suggests that this diagnosis should be considered in patients of any age with an appropriate clinical picture. We recommend IVIG as a first line therapy for adult cases of Rasmussen's encephalitis.