Ethnic differences in bladder cancer survival.
Ethnic differences in bladder cancer survival.
复制标题
DOI：
10.1016/j.urology.2011.02.042
复制
发表时间：
2011-09
期刊：
影响因子：
2.1
通讯作者：
Elkin EB
中科院分区：
文献类型：
--
作者：
Yee DS;Ishill NM;Lowrance WT;Herr HW;Elkin EB
膀胱癌预后的种族差异有文献记载，黑人生存率较低。膀胱癌在其他少数民族人群中的预后没有得到很好的描述。我们研究了30年来美国白人、黑人、西班牙裔和亚洲/太平洋岛民膀胱癌生存率的趋势。从监测、流行病学和最终结果癌症登记数据中，我们确定了1975年至2005年间诊断为膀胱移行细胞癌的患者。该队列包括163,973名白人，7,731名黑人，7,364名西班牙裔和5,934名亚洲/太平洋岛民患者。我们评估了种族和患者特征之间的关系。估计每个种族和分期和分级亚组的疾病特异性5年生存率。黑人比白人、西班牙裔和亚洲/太平洋岛民表现出更高的疾病阶段，尽管随着时间的推移，在所有群体中都观察到早期表现的趋势。黑人的5年疾病特异性生存率一直低于其他种族，即使按阶段和年级分层也是如此。白人的5年疾病特异性生存率为82.8%，黑人为70.2%，西班牙裔为80.7%，亚洲/太平洋岛民为81.9%。随着时间的推移，黑人患者存在持续的疾病特异性生存劣势，这在其他种族群体中没有发现。膀胱癌存活率的种族差异在白人和黑人之间持续存在，而其他少数民族的存活率似乎与白人相似。为了更好地理解这些差异，需要进一步研究黑人患者获得护理、护理质量和治疗决策的途径。
Racial disparities in bladder cancer outcomes have been documented with poorer survival observed among blacks. Bladder cancer outcomes in other ethnic minority groups are less well described. We examined trends in bladder cancer survival among whites, blacks, Hispanics, and Asian/Pacific Islanders in the US over a 30-year period. From the Surveillance, Epidemiology and End Results cancer registry data, we identified patients diagnosed with transitional cell carcinoma of the bladder between 1975 and 2005. This cohort included 163,973 white, 7,731 black, 7,364 Hispanic and 5,934 Asian/Pacific Islander patients. We assessed the relationship between ethnicity and patient characteristics. Disease-specific 5-year survival was estimated for each ethnic group and for subgroups of stage and grade. Blacks presented with higher stage disease than whites, Hispanics and Asian/Pacific Islanders, although a trend toward earlier stage presentation was observed in all groups over time. Five-year disease-specific survival was consistently worse for blacks than for other ethnic groups, even when stratified by stage and grade. Five-year disease-specific survival was 82.8% in whites compared with 70.2% in blacks, 80.7% in Hispanics and 81.9% in Asian/Pacific Islanders. There was a persistent disease-specific survival disadvantage in black patients over time which was not seen in the other ethnic groups. Ethnic disparities in bladder cancer survival persist between whites and blacks, while survival in other ethnic minority groups appears similar to that of whites. Further study of access to care, quality of care and treatment decision making among black patients is needed to better understand these disparities.
登录
查看更多内容
影响因子：
6.2
作者：
Gore, JL;Kwan, L;Litwin, MS
通讯作者：
Litwin, MS
DOI：
10.1093/jnci/95.8.588
发表时间：
2003-04-16
期刊：
JOURNAL OF THE NATIONAL CANCER INSTITUTE
影响因子：
--
作者：
Schrag, D;Hsieh, LJ;Begg, CB
通讯作者：
Begg, CB
影响因子：
120.7
作者：
Begg, CB;Cramer, LD;Brennan, MF
通讯作者：
Brennan, MF
影响因子：
6.6
作者：
Miller, DC;Taub, DA;Wei, JT
通讯作者：
Wei, JT
影响因子：
6.2
作者：
Scosyrev, Emil;Noyes, Katia;Messing, Edward
通讯作者：
Messing, Edward