Performance of OptiMAL-IT® compared to microscopy, for malaria detection in Burkina Faso
Performance of OptiMAL-IT® compared to microscopy, for malaria detection in Burkina Faso
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DOI：
10.1111/j.1365-3156.2009.02228.x
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发表时间：
2009-03-01
影响因子：
3.3
通讯作者：
d'Alessandro, Umberto
中科院分区：
文献类型：
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作者：
Valea, Innocent;Tinto, Halidou;d'Alessandro, Umberto
比较布基纳法索疟疾快速诊断检测方法OptiMAL-IT (R)与显微镜检测方法的性能。采用显微镜和OptiMAL-IT (R)对464名疑似疟疾住院儿童的手指刺血样本进行疟疾检测。OptiMAL-IT (R)的敏感性为98.7% (CI 95% = 97.6 ~ 99.8)，特异性为96.2% (CI 95% = 94.3 ~ 98.1)，阳性似然比较高（25.97）。OptiMAL-IT (R)可被认为是布基纳法索诊断疟疾的一种好方法，特别是在很少或无法获得显微镜服务的偏远地区。
To compare the performance of OptiMAL-IT (R), a rapid diagnostic test for malaria, with that of microscopy in Burkina Faso.Finger-prick blood samples of 464 children attending hospital for suspected malaria were tested for malaria by microscopy and OptiMAL-IT (R).The sensitivity and specificity of OptiMAL-IT (R) were 98.7% (CI 95% = 97.6-99.8) and 96.2% (CI 95% = 94.3-98.1) respectively, with a high positive likelihood ratio (25.97).OptiMAL-IT (R) can be considered a good method to diagnose malaria in Burkina Faso, particularly in remote areas with little or no access to microscopy services.