Limitations of claims and registry data in surgical oncology research
Limitations of claims and registry data in surgical oncology research
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DOI：
10.1245/s10434-007-9658-3
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发表时间：
2008-02-01
影响因子：
3.7
通讯作者：
Pawlik, Timothy M.
中科院分区：
文献类型：
--
作者：
Nathan, Hari;Pawlik, Timothy M.
基于大量基于人群的数据集（例如行政索赔数据和肿瘤登记数据）的研究在外科肿瘤学研究中已变得越来越普遍。这些数据集可以相对容易地获取，并且与机构数据相比，它们提供了更大的样本量和更高的普遍性。然而，在分析和解释此类数据时必须考虑到一些重大限制。如果对数据质量和深度、潜在偏差来源、缺失数据、I 类错误和统计显着性评估等问题关注不够，可能会导致无效结论。本文回顾了基于人群的数据集的一些重要局限性以及用于分析它们的方法。文献中对这些问题的坦率报告以及外科肿瘤学家对这些局限性的认识的提高将确保外科肿瘤学文献中基于人群的研究达到高标准的方法学质量和临床实用性。
Studies based on large population-based data sets, such as administrative claims data and tumor registry data, have become increasingly common in surgical oncology research. These data sets can be acquired relatively easily, and they offer larger sample sizes and improved generalizability compared with institutional data. There are, however, significant limitations that must be considered in the analysis and interpretation of such data. Invalid conclusions can result when insufficient attention is paid to issues such as data quality and depth, potential sources of bias, missing data, type I error, and the assessment of statistical significance. This article reviews some important limitations of population-based data sets and the methods used to analyze them. The candid reporting of these issues in the literature and an increased awareness among surgical oncologists of these limitations will ensure that population-based studies in the surgical oncology literature achieve high standards of methodological quality and clinical utility.