Conditionally immortalized cell lines as model systems for high-throughput biology in drug discovery
Conditionally immortalized cell lines as model systems for high-throughput biology in drug discovery
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DOI：
10.1042/bst0300800
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发表时间：
2002-08-01
影响因子：
3.9
通讯作者：
Shepherd, PR
中科院分区：
文献类型：
--
作者：
Daniele, N;Halse, R;Shepherd, PR
There is an increasing emphasis on the need for high-quality biological data much earlier in the drug-discovery process. This has led to the development of high-throughput approaches to biology, many of which rely on the use of cell-culture models. Unfortunately, available cell-culture models often reflect poorly the characteristics of the tissue they are supposed to represent. However, the conditional-immortalization approach as applied by Xcellsyz offers the possibility of producing human cell lines on demand, which are truly representative of the tissue from which they derive.
