A randomized trial on the effect of a multimodal intervention on physical capacity, functional performance and quality of life in adult patients undergoing allogeneic SCT
A randomized trial on the effect of a multimodal intervention on physical capacity, functional performance and quality of life in adult patients undergoing allogeneic SCT
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DOI：
10.1038/bmt.2009.27
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发表时间：
2009-05-01
影响因子：
4.8
通讯作者：
Adamsen, L.
中科院分区：
文献类型：
--
作者：
Jarden, M.;Baadsgaard, M. T.;Adamsen, L.
这项随机对照试验的目的是研究4- 6周的多模式运动、放松和心理教育对同种异体造血细胞移植成人受者的身体能力、功能表现和生活质量（QOL）的影响。总共有42名患者被随机分配到有监督的多模式干预组或接受常规护理的对照组。主要终点是VO2 max测量的有氧能力。次要终点是肌力、功能表现、体力活动水平、生活质量、疲劳、心理健康和临床结果。多模式干预对身体能力有显著影响：最大摄氧量（VO2 max）
The aim of this randomized controlled trial was to investigate the effect of a 4- to 6-week multimodal program of exercise, relaxation and psychoeducation on physical capacity, functional performance and quality of life (QOL) in allogeneic hematopoietic cell transplantation (allo-HSCT) adult recipients. In all, 42 patients were randomized to a supervised multimodal intervention or to a control group receiving usual care. The primary end point was on aerobic capacity measured in VO2 max. Secondary end points were muscle strength, functional performance, physical activity level, QOL, fatigue, psychological well-being and clinical outcomes. The multimodal intervention had a significant effect on physical capacity: VO2 max (P