Predialysis management of divalent ion metabolism.
Predialysis management of divalent ion metabolism.
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二价离子代谢的透析前管理。
DOI：
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发表时间：
1999
期刊：
影响因子：
--
通讯作者：
A. Hutchison
中科院分区：
文献类型：
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作者：
A. Hutchison
二价离子代谢紊乱起源于肾损害的早期阶段。早期干预是必要的，以尽量减少其影响，特别是在最近的报告表明，血磷和透析患者的相对死亡风险之间的关联。随着接受肾脏替代治疗的患者年龄和合并症的增加，其管理的复杂性也增加。专门的“透析前”使多学科团队能够以有序和适当的方式进行干预，以延迟进展，改善合并症，预防尿毒症并发症，并为透析和肾移植做好患者的身心准备。这一过程的一部分涉及到肾性骨营养不良的骨骼和生化并发症的高风险患者的识别。纠正低钙血症，酸中毒，高磷血症和PTH水平上升应迅速实现。口服骨化三醇治疗通常是必要的，需要仔细监测和监督。
Disordered divalent ion metabolism has its origins in the earliest stages of renal impairment. Early intervention is essential to minimize its effects, especially in the light of recent reports demonstrating an association between serum phosphate and relative risk of mortality in dialysis patients. As the age and comorbidity of patients accepted for renal replacement therapy increases, the complexity of their management also increases. A dedicated "predialysis" enables a multidisciplinary team to intervene in an orderly and appropriate fashion to delay progression, modify comorbidity, prevent uraemic complications and prepare the patient mentally and physically for dialysis and renal transplantation. Part of this process involves the identification of patients at high risk of the skeletal and biochemical complications of renal osteodystrophy. Correction of hypocalcemia, acidosis, hyperphosphatemia and rising PTH levels should be achieved quickly. Oral calcitriol therapy is frequently necessary, and requires careful monitoring and supervision.
脉冲口服骨化三醇治疗连续不卧床腹膜透析患者的甲状旁腺功能亢进症：初步观察。
DOI：
10.1016/s0272-6386(12)80832-8
发表时间：
1992
期刊：
American journal of kidney diseases : the official journal of the National Kidney Foundation
影响因子：
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作者：
Martin,KJ;Ballal,HS;Domoto,DT;Blalock,S;Weindel,M
通讯作者：
Weindel,M