Lymphocyte and cytokine responses of young cattle during primary infection with Fasciola hepatica

Lymphocyte and cytokine responses of young cattle during primary infection with Fasciola hepatica
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DOI:
10.1016/s0034-5288(98)90171-0
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发表时间:
1998-09-01
影响因子:
2.4
通讯作者:
Mulcahy, G
Mulcahy, G
中科院分区:
农林科学3区
文献类型:
--
作者:
Clery, DG;Mulcahy, G

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An experiment was designed to characterise the early immune responses of cattle given a trickle infection of the trematode Fasciola hepatica. Lymphocyte responses and IFN-gamma production following stimulation with Fasciola antigens were measured. Animals were sequentially slaughtered at weeks 5, 7, 9 and 11 post-infection. Results demonstrated responses to fluke antigens and cytokine production (IFN gamma) from weeks 2-5 post-infection. These findings may suggest an early stimulation of IFN gamma production by peripheral blood lymphocytes following infection with F hepatica in cattle.