QUALITATIVE AND QUANTITATIVE-ANALYSIS OF THE PHENOLIC CONSTITUENTS FROM ORTHOSIPHON-ARISTATUS

QUALITATIVE AND QUANTITATIVE-ANALYSIS OF THE PHENOLIC CONSTITUENTS FROM ORTHOSIPHON-ARISTATUS
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DOI:
10.1055/s-2006-960060
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发表时间:
1991-04-01
期刊:
影响因子:
2.7
通讯作者:
HARTMANN, T
HARTMANN, T
中科院分区:
医学3区
文献类型:
--
作者:
SUMARYONO, W;PROKSCH, P;HARTMANN, T

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研究了毛管草(Orthosiphonis folium DAB 9)的酚类成分.根据其光谱特征分离鉴定了20个化合物。这些化合物包括9种亲脂性黄酮、2种黄酮醇糖苷和9种咖啡酸衍生物。最近报道的甲基利pariochromene A的存在无法得到证实。通过HPLC定量鉴定的所有化合物。咖啡酸衍生物,包括主要化合物迷迭香酸和2,3-二咖啡酰酒石酸(67%的总确定的酚类化合物)占主导地位的黄酮类化合物(33%)的含水甲醇提取物。咖啡酸衍生物的优势在热水提取物中甚至更明显(占总鉴定酚类的94.5%),其与草药茶相当。
Orthosiphon aristatus (Orthosiphonis folium DAB 9) was studied with regard to its phenolic constituents. Twenty compounds were isolated and identified on the basis of their spectral characteristics. The compounds included nine lipophilic flavones, two flavonol glycosides, and nine caffeic acid derivatives. The presence of the recently reported methylripariochromene A could not be confirmed. All compounds identified were quantified by HPLC. The caffeic acid derivatives including the major compounds rosmarinic acid and 2,3-dicaffeoyltartaric acid (67% of total identified phenolics) predominated over the flavones (33%) in an aqueous MeOH extract. The predominance of the caffeic acid derivatives was even more pronounced in a hot water extract (94.5% of total identified phenolics) that was comparable to a herbal tea.