Sequential one-pot combination of multi-component and multi-catalysis cascade reactions: an emerging technology in organic synthesis

Sequential one-pot combination of multi-component and multi-catalysis cascade reactions: an emerging technology in organic synthesis
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DOI:
10.1039/c0ob00611d
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发表时间:
2011-01-01
影响因子:
3.2
通讯作者:
Jain, Sangeeta
Jain, Sangeeta
中科院分区:
化学3区
文献类型:
--
作者:
Ramachary, Dhevalapally B.;Jain, Sangeeta

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创建多组分反应 (MCR) 和多催化级联 (MCC) 反应的连续一锅组合是一项具有挑战性的任务,已成为合成有机化学中的一项新技术。通过MCR/MCC反应的一锅顺序组合,可以以更少的浪费和更大的经济效益生产出为我们的生活增加价值的化学产品(精细化学品、农用化学品和药品)。在这个新兴领域,我们描述了我们最近对连续一锅 MCR/MCC 反应的开发和设计,以促进它们在有机化学中作为仿生学的实现。
Creating sequential one-pot combinations of multi-component reactions (MCRs) and multi-catalysis cascade (MCC) reactions is a challenging task that has already emerged as a new technology in synthetic organic chemistry. Through one-pot sequential combination of MCRs/MCC reactions, the chemical products (fine chemicals, agrochemicals and pharmaceuticals) that add value to our lives can be produced with less waste and greater economic benefits. Within this Emerging Area, we describe our recent developments and designs for sequential one-pot MCRs/MCC reactions to facilitate their realization as biomimetics in organic chemistry.