Adenocarcinoma of the parotid gland with calcification
Adenocarcinoma of the parotid gland with calcification
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DOI：
10.1259/dmfr/54388937
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发表时间：
2003-03-01
影响因子：
3.3
通讯作者：
Koh, KJ
中科院分区：
文献类型：
--
作者：
Song, HU;Kwon, KJ;Koh, KJ
一位78岁的韩国女性被转诊到全北国立大学牙科医院，主诉面部麻痹和右侧腮腺区可触及肿块4年。临床检查显示，由于右侧腮腺区域有一个4 cm x 5 cm的硬、固定、无压痛肿块，眼睛闭合不全，嘴角轻微震颤，导致面部外观不对称。全景X线片显示下颌后支上有一个无定形钙化肿块，邻近肿块的锥形板变薄。涎管造影显示主管收缩，条纹管、闰管和实质区无进一步充盈。电脑断层显示一个扩张性肿块，并有轻微的对比增强，累及右侧腮腺。大肿块内可见坏死区及钙化灶。骨扫描显示Tc-99（m）-亚甲基二膦酸盐在右后上颌骨上明显蓄积。显微镜检查结果显示肿瘤细胞内极轻微的形态学改变和罕见的有丝分裂像，病变被诊断为腺癌，未另行说明（NOS，II级）。
A 78-year-old Korean woman was referred to Chonbuk National University Dental Hospital complaining of facial palsy and palpable mass in the right parotid gland area for 4 years. Clinical examination showed an asymmetrical facial appearance due to a 4 cm x 5 cm hard, fixed, non-tender mass in the right parotid gland area, incomplete eye closure and a slight tremor at the corner of the mouth. A panoramic radiograph showed an amorphous calcified mass on the posterior mandibular ramus with thinning of the conical plate adjacent to the mass. A sialogram showed constriction of the main duct and no further filling of striated, intercalated ducts and parenchymal areas. CT indicated an expansile mass with slight contrast enhancement involving the right parotid gland. The large mass showed necrotic areas and calcifications. A bone scan showed marked accumulation of Tc-99(m)-methylene diphosphonate on the right posterior maxilla. Microscopic findings revealed minimal morphological alterations and rare mitotic figures within tumour cells, and the lesion was diagnosed as adenocarcinoma not otherwise specified (NOS, grade II).