Population-based studies of AD: message and methods: an epidemiologic view
Population-based studies of AD: message and methods: an epidemiologic view
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DOI：
10.1002/sim.1708
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发表时间：
2004-01-30
影响因子：
2
通讯作者：
Brock, DB
中科院分区：
文献类型：
--
作者：
Launer, LJ;Brock, DB
痴呆症是一个日益严重的公共卫生问题，因为随着人口老龄化，患有这种疾病的人数正在迅速增加。在过去的十年中，发起了几项基于人口的纵向研究，目前仍在进行中。这些研究将为痴呆症的危险因素和进展提供有价值的见解。然而，有几个设计和统计上的挑战，是独特的研究人口中的痴呆症，需要加以解决。这些挑战包括疾病的确定和暴露的定义。为了减少前瞻性流行病学研究的偏倚，不仅需要新的疾病和暴露定义方法，而且可能还需要新的流行病学或统计学方法。John Wiley Sons，Ltd.于2004年出版
Dementia is a growing public health problem because the numbers suffering the disease is increasing rapidly as the population ages. Over the past decade several longitudinal population-based studies were initiated and are still on-going. These studies will provide valuable insight into the risk factors for, and progression of dementia. However, there are several design and statistical challenges that are unique to studying dementia in the population and that need to be addressed. These challenges include aspects of both ascertainment of disease and definition of exposure. To reduce bias from prospective epidemiologic studies, not only are new approaches to definition of disease and exposure needed, but new epidemiologic or statistical methods may be required as well. Published in 2004 by John Wiley Sons, Ltd.