Cerebral folate deficiency
Cerebral folate deficiency
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DOI：
10.1017/s0012162204001471
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发表时间：
2004-12-01
影响因子：
3.8
通讯作者：
Blau, N
中科院分区：
文献类型：
--
作者：
Ramaekers, VT;Blau, N
脑叶酸缺乏(CFD)可定义为神经系统外叶酸代谢正常的情况下，与脑脊液(CSF)活性叶酸代谢产物5-甲基四氢叶酸(5MTHF)低相关的任何神经综合征。CFD可能是由于叶酸转运障碍或中枢神经系统(CNS)内叶酸周转增加所致。
Cerebral folate deficiency (CFD) can be defined as any neurological syndrome associated with low cerebrospinal fluid (CSF) 5-methyltetrahydrofolate (5MTHF), the active folate metabolite, in the presence of normal folate metabolism outside the nervous system. CFD could result from either disturbed folate transport or from increased folate turnover within the central nervous system (CNS).