Peristaltic movement evoked in intestinal tube devoid of mucosa and submucosa.
Peristaltic movement evoked in intestinal tube devoid of mucosa and submucosa.
复制标题
在没有粘膜和粘膜下层的肠管中引起蠕动。
DOI：
10.2170/jjphysiol.42.363
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发表时间：
1992
期刊：
影响因子：
--
通讯作者：
S. Yokoyama
中科院分区：
文献类型：
--
作者：
S. Tsuji;P. Anglade;T. Ozaki;T. Sazi;S. Yokoyama
在豚鼠回肠管的制备过程中，用机械方法刮除粘膜和粘膜下层，对录像记录的粘连进行计算机分析。与仅刮除粘膜的回肠管和正常回肠管相比，回肠管诱发回肠梗阻的阈值更高，回肠梗阻的传导速度更慢，蠕动力更弱。标本组织学对照证明，分离的环行肌表面无粘膜下神经丛神经细胞体。结论是，虽然受损，但可以通过由肌间神经元的神经回路组成的反射弓的激活来引起，该反射弓应该是由外肌层中的牵张感受器的兴奋产生的。
Computerized analysis of video-recorded peristalsis was made in a preparation of guinea-pig ileum tube from which both mucosa and submucosa were mechanically scraped off. Threshold value for provoking peristalsis was higher, conduction velocity of peristalsis was slower, and peristaltic force was weaker in comparison with the ileum tube from which only mucosa was scraped off and with the normal ileum tube. A histological control of the preparation proved that there was no nerve cell body of submucous plexus on the surface of separated circular muscle. It was concluded that peristalsis, though impaired, could be provoked by way of activation of the reflex arch consisted by neural circuit of myenteric neurons which should be produced by excitation of stretch receptors in the muscularis externa.