Muscle activity localization with 31P spectroscopy and calculated T2-weighted 1H images.
Muscle activity localization with 31P spectroscopy and calculated T2-weighted 1H images.
复制标题
使用 31P 光谱和计算的 T2 加权 1H 图像进行肌肉活动定位。
DOI:
10.1097/00004424-199104000-00005
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发表时间:
1991
影响因子:
6.7
通讯作者:
MacFall,JR
中科院分区:
文献类型:
--
作者:
Weidman,ER;Charles,HC;Negro-Vilar,R;Sullivan,MJ;MacFall,JR
Using 31 spectroscopy and magnetic resonance imaging (MRI), the authors studied changes in muscle phosphorous metabolites and T2 with isometric knee extension to evaluate the potential role of T2 images in coil placement for exercise spectroscopy studies. Increased signal intensity was visible in active muscles on T2 images after exercise. Calculated T2-weighted values were elevated immediately after exercise in the quadriceps (P<. 01). T2 increases for individual quadricep muscles varied, with the largest changes in the rectus femoris and the least in the vastus lateralis. 31 P spectroscopy studies demonstrated similar findings; percent change in T2 correlated positively with inorganic phosphorus to phosphocreatine ratio (Pi/PCr)(r= 0.89, P<. 01) and negatively with pH (r=-0.88, P<. 01). The correlations between imaging and spectroscopy suggest that T2 images may allow more precise placement of phosphorous coils in exercise studies. The heterogeneity of T2 changes within the quadriceps with exercise suggests that assumptions about muscle activity may be misleading. T2 images may provide muscle activity verification for exercise studies.