Muscle activity localization with 31P spectroscopy and calculated T2-weighted 1H images.

Muscle activity localization with 31P spectroscopy and calculated T2-weighted 1H images.
复制标题

使用 31P 光谱和计算的 T2 加权 1H 图像进行肌肉活动定位。

DOI:
10.1097/00004424-199104000-00005
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发表时间:
1991
影响因子:
6.7
通讯作者:
MacFall,JR
MacFall,JR
中科院分区:
医学1区
文献类型:
--
作者:
Weidman,ER;Charles,HC;Negro-Vilar,R;Sullivan,MJ;MacFall,JR

文献摘要

被引文献

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使用31光谱和磁共振成像(MRI),作者研究了肌肉磷代谢物和等长膝关节伸展的T2变化,以评价T2图像在运动光谱研究线圈放置中的潜在作用。运动后T2图像上活动肌肉的信号强度增加。计算的T2加权值在运动后即刻在股四头肌中升高(P<. 01)。每个四头肌的T2增加各不相同,股直肌的变化最大,股外侧肌的变化最小。~(31)P能谱研究也显示了类似的结果,T_2变化百分比与无机磷/磷酸肌酸比值(Pi/PCr)呈正相关(r= 0.89,P<0.01)。01)与pH呈负相关(r=-0.88,P <. 01)。成像和光谱学之间的相关性表明,T2图像可能允许在运动研究中更精确地放置磷线圈。运动时股四头肌内T2变化的异质性表明,关于肌肉活动的假设可能是误导性的。T2图像可以为运动研究提供肌肉活动验证。
Using 31 spectroscopy and magnetic resonance imaging (MRI), the authors studied changes in muscle phosphorous metabolites and T2 with isometric knee extension to evaluate the potential role of T2 images in coil placement for exercise spectroscopy studies. Increased signal intensity was visible in active muscles on T2 images after exercise. Calculated T2-weighted values were elevated immediately after exercise in the quadriceps (P<. 01). T2 increases for individual quadricep muscles varied, with the largest changes in the rectus femoris and the least in the vastus lateralis. 31 P spectroscopy studies demonstrated similar findings; percent change in T2 correlated positively with inorganic phosphorus to phosphocreatine ratio (Pi/PCr)(r= 0.89, P<. 01) and negatively with pH (r=-0.88, P<. 01). The correlations between imaging and spectroscopy suggest that T2 images may allow more precise placement of phosphorous coils in exercise studies. The heterogeneity of T2 changes within the quadriceps with exercise suggests that assumptions about muscle activity may be misleading. T2 images may provide muscle activity verification for exercise studies.