Treatment of acquired bilateral nevus of Ota-like macules (Hori's nevus) using 1064-nm Q-switched Nd:YAG laser with low fluence
Treatment of acquired bilateral nevus of Ota-like macules (Hori's nevus) using 1064-nm Q-switched Nd:YAG laser with low fluence
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DOI：
10.1111/j.1365-4632.2008.04061.x
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发表时间：
2009-12-01
影响因子：
3.6
通讯作者：
Bu, Tae Sung
中科院分区：
文献类型：
--
作者：
Cho, Sung Bin;Park, Soo Jie;Bu, Tae Sung
背景获得性双侧太田痣样斑（ABNOM）或Hori氏痣是亚洲人常见的皮肤黑素细胞色素沉着过度。目的描述1064-nm Q开关Nd：YAG激光（QSNY）低能量对韩国ABNOM患者的疗效。（13名女性和2名男性;平均年龄，33.2岁;范围，26-52岁;菲茨帕特里克皮肤类型IV），临床诊断为ABNOM，并使用1064 nm QSNY低通量治疗，入组本研究。使用MedLite C6（TM）（HoyaConBio Inc.，Fremont，CA，USA）以1-2周的间隔给药。激光设置为2.2-2.6 J/cm 2，使用6毫米的光斑尺寸，其次是4-6 J/cm 2，使用4毫米的光斑尺寸。ResultsThe中位数的QSNY治疗会话为11（范围，10-15）。最终治疗后2个月的随访结果显示，15例患者中有7例（46.7%）显示临床改善76- 100%，5例（33.3%）显示临床改善51- 75%。3例患者显示中度临床改善，介于26%和50%之间。治疗后的dyschromia，包括hypo-和色素沉着过度，没有observed.ConclusionWe建议，QSNY与低通量提供了一个易于执行，低停机时间，有效的治疗算法在某些情况下ABNOM在亚洲患者。
BackgroundAcquired bilateral nevus of Ota-like macules (ABNOM), or Hori's nevus, is a common dermal melanocytic hyperpigmentation in Asians.AimTo describe the effect of 1064-nm Q-switched Nd:YAG laser (QSNY) with low fluence in South Korean patients with ABNOM.MethodsFifteen South Korean patients (13 women and two men; mean age, 33.2 years; range, 26-52 years; Fitzpatrick skin type IV), clinically diagnosed with ABNOM, and treated using 1064-nm QSNY with low fluence, were enrolled in this study. Patients were treated with 1064-nm QSNY using a MedLite C6 (TM) (HoyaConBio Inc., Fremont, CA, USA) at 1-2-week intervals. The laser settings were 2.2-2.6 J/cm2 using a 6-mm spot size, followed by 4-6 J/cm2 using a 4-mm spot size.ResultsThe median number of QSNY treatment sessions was 11 (range, 10-15). Follow-up results 2 months after the final treatment revealed that seven of the 15 patients (46.7%) demonstrated clinical improvement of 76-100%, and five (33.3%) of 51-75%. Three patients showed moderate clinical improvement between 26% and 50%. Post-therapy dyschromia, including hypo- and hyperpigmentation, was not observed.ConclusionWe suggest that QSNY with low fluence provides an easy-to-perform, low-downtime, effective treatment algorithm in certain cases of ABNOM in Asian patients.