Cerebral Oxygenation, Extraction, and Autoregulation in Very Preterm Infants Who Develop Peri-Intraventricular Hemorrhage

Cerebral Oxygenation, Extraction, and Autoregulation in Very Preterm Infants Who Develop Peri-Intraventricular Hemorrhage
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DOI:
10.1016/j.jpeds.2012.09.038
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发表时间:
2013-04-01
影响因子:
5.1
通讯作者:
van Bel, Frank
van Bel, Frank
中科院分区:
医学2区
文献类型:
--
作者:
Alderliesten, Thomas;Lemmers, Petra M. A.;van Bel, Frank

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目的验证近红外光谱(NIRS)测定的区域脑氧饱和度(rScO(2))、脑组织分数氧提取(cFTOE)和自身调节能力模式对新生儿发生脑室周围内出血(PIVH)风险的识别作用。本病例对照研究是对入院12小时后出现PIVH的30名新生儿的亚分析,该研究是一项更大的前瞻性观察队列研究的一部分,该研究包括650名出生在北京的早产儿
Objective To test the hypothesis that near-infrared spectroscopy (NIRS)-determined patterns of regional cerebral oxygen saturation (rScO(2)), cerebral fractional tissue oxygen extraction (cFTOE), and autoregulatory ability can identify neonates at risk for developing peri-intraventricular hemorrhage (PIVH).Study design This case-control study is a subanalysis of 30 neonates who developed PIVH > 12 hours after admission as part of a lager prospective observational cohort study comprising 650 preterm neonates born at