Continent orthotopic ileal neobladder after kidney transplantation in a patient with urothelial cell carcinoma associated with chinese herb nephropathy
Continent orthotopic ileal neobladder after kidney transplantation in a patient with urothelial cell carcinoma associated with chinese herb nephropathy
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DOI：
10.1016/j.transproceed.2008.02.089
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发表时间：
2008-06-01
影响因子：
0.9
通讯作者：
Tanabe, K.
中科院分区：
文献类型：
--
作者：
Shirakawa, H.;Ishida, H.;Tanabe, K.
58岁男性，因中草药肾病终末期肾病，于2002年11月14日行肾移植手术。继续使用他克莫司、霉酚酸酯和甲基强的松龙进行免疫抑制治疗。他被诊断为右输尿管癌，并于2003年12月13日接受了右肾输尿管切除术。2004年3月5日因左输尿管癌行左肾输尿管切除术。随后，他被诊断患有多发性膀胱癌和原位癌。8月31日，患者行原位回肠新膀胱根治性切除术（Studer法）。术后过程平淡无奇。随访3年后，患者无复发迹象，血清肌酐水平稳定（1.7 mg/dL）。在白天和晚上都保持克制；他没有间断的自我导尿。我们认为原位回肠新膀胱是肾移植受者膀胱切除术后尿转移的安全方法。
A 58-year-old man underwent kidney transplantation on November 14, 2002 for end-stage kidney disease after Chinese herb nephropathy. Immunosuppressive therapy was maintained with tacrolimus, mycophenolate mofetil, and methylpredonisolone. He was diagnosed with right ureteral cancer and underwent right nephroureterectomy on December 13, 2003. Then, he underwent left nephroureterectomy for left ureteral cancer on March 5, 2004. Subsequently, he was diagnosed with multiple bladder cancers and carcinoma in situ. On August 31, he underwent radical cystectomy with an orthotopic ileal neobladder (Studer's method). The postoperative course was uneventful. After 3 years follow-up, this patient shows no evidence of recurrence and his serum creatinine level is stable (1.7 mg/dL). The continence is maintained during both day and night; he voids without intermittent self-catheterization. We suggest that an orthotopic ileal neobladder is a safe method of urinary diversion after cystectomy in kidney transplant recipients.