Material Chemistry of Two-Dimensional Inorganic Nanosheets in Cancer Theranostics
Material Chemistry of Two-Dimensional Inorganic Nanosheets in Cancer Theranostics
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DOI：
10.1016/j.chempr.2018.02.012
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发表时间：
2018-06
期刊：
影响因子：
23.5
通讯作者：
Bowen Yang;Yu Chen;Jianlin Shi
中科院分区：
文献类型：
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作者：
Bowen Yang;Yu Chen;Jianlin Shi
近年来，二维（2D）化学的发展使得二维无机纳米材料的研究在凝聚态物理、材料科学、化学、生物学和纳米技术等领域得到了迅速发展。作为一个特殊的跨学科研究前沿，二维无机纳米片的肿瘤应用，能够实现理想的治疗诊断性能，近年来引起了科学界的极大关注。在这篇综述中，我们总结了基本原则的2D无机家庭的材料化学在癌症治疗诊断和纳米使能融合的材料化学和肿瘤学的基础上的治疗诊断平台的最新进展的基础上，2D无机纳米片。此外，目前的挑战和发展的2D无机纳米片进一步临床翻译的前景也进行了讨论。预计这种新兴的2D无机家族将在下一代癌症治疗诊断学中发挥重要作用。
Recent advances in two-dimensional (2D) chemistry have led to the rapid development of research on the emerging 2D inorganic nanomaterials in various fields, such as condensed matter physics, material science, chemistry, biology, and nanotechnology. As a special cross-disciplinary research frontier, 2D inorganic nanosheets for oncological applications, which are capable of accomplishing desirable theranostic performance, have attracted great attention from the scientific community in recent years. In this review, we summarize the underlying fundamental principles for the material chemistry of the 2D inorganic family in cancer theranostics and nano-enabled amalgamation of material chemistry and oncology on the basis of the recent progress in theranostic platforms based on 2D inorganic nanosheets. Moreover, current challenges and perspectives on the development of 2D inorganic nanosheets for further clinical translations are also discussed. It is expected that this emerging 2D inorganic family will play a vital role in next-generation cancer theranostics.