Embryonic stem cells in cardiac repair and regeneration.
Embryonic stem cells in cardiac repair and regeneration.
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DOI:
10.1089/ars.2009.2491
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发表时间:
2009-08
影响因子:
6.6
通讯作者:
Singla DK
中科院分区:
文献类型:
--
作者:
Singla DK
Cell transplantation is a fast growing research with a potential of therapeutic approach for the treatment of heart diseases. Clinical applications require preparation of large number of donor cells. Stem cell studies published todate demonstrate that scientist have not reached at the general consensus to use optimal cell type for better cardiac repair and regeneration. We use embryonic stem (ES) cells and their released factors for cardiac repair and regeneration. The major concern of cardiac regeneration using stem cells includes engraftment, differentiation and teratoma formation following ES cell transplantation. Our current knowledge of ES cell transplantation in the heart is very limited. This review will discuss the use of various growth factors to enhance ES cells engraftment and differentiation as well as the issue of teratoma formation.
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影响因子:
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作者:
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通讯作者:
Robbins, RC
DOI:
10.1111/j.1443-9573.2006.00253.x
发表时间:
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期刊:
Chinese journal of digestive diseases
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