A to Z of Zika Virus: A Comprehensive Review for Clinicians.

A to Z of Zika Virus: A Comprehensive Review for Clinicians.
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DOI:
10.1177/2333794x20919595
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发表时间:
2020-01-01
影响因子:
2.2
通讯作者:
Arora, Harbir Singh
Arora, Harbir Singh
中科院分区:
其他
文献类型:
--
作者:
Arora, Harbir Singh

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自2007年在太平洋(YAP群岛和密克罗尼西亚联邦)首次爆发以来,寨卡病毒于2015年逐渐蔓延至美洲。该病毒的嗜神经性特征于2015年在巴西爆发期间首次被发现。通过强调预防寨卡病毒在孕妇中传播的重要性的研究,发现越来越多出生时患有小头畸形和其他先天性畸形的婴儿。与此次暴发时相比,现在对出生时感染该病毒的婴儿的长期结局有了更好的了解。这篇综述的主题包括寨卡病毒的历史、传播方式、疑似病例的诊断、病理生理学、并发症和预防寨卡病毒感染。
Since its first outbreak in 2007 in the Pacific (Yap islands and Federal States of Micronesia), Zika virus has gradually and recently spread to the Americas in 2015. The neurotropic character of the virus was first noted during this outbreak in Brazil in 2015. Increasing number of infants born with microcephaly and other congenital deformities were identified through studies that have highlighted the importance of prevention of transmission of Zika virus in pregnant women. Long-term outcomes in infants born with this infection are now better understood than at the time of onset of this outbreak. Topics covered in this review include the history, modes of transmission, diagnosis of suspected cases, pathophysiology, complications, and prevention of Zika virus infection.