Ratiometric Fluorescence Imaging of Cellular Glutathione

Ratiometric Fluorescence Imaging of Cellular Glutathione
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DOI:
10.1021/ol200967w
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发表时间:
2011-06-03
期刊:
影响因子:
5.2
通讯作者:
Kim, Hae-Jo
Kim, Hae-Jo
中科院分区:
化学1区
文献类型:
--
作者:
Kim, Gun-Joong;Lee, Kiwon;Kim, Hae-Jo

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设计了一种带有氢键的荧光探针(1)来检测谷胱甘肽。该探针通过Michael反应对谷胱甘肽表现出快速的比例荧光反应,使我们能够获得谷胱甘肽清晰的细胞图像。
A fluorescent probe (1) with a hydrogen bond was designed for the detection of GSH. The probe exhibited a rapid and ratiometric fluorescence response to GSH through a Michael reaction and allowed us to obtain clear cellular images for GSH.