A comparison of microarray databases.
A comparison of microarray databases.
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DOI：
10.1093/bib/2.2.143
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发表时间：
2001-05-01
影响因子：
9.5
通讯作者：
Littlejohn, T G
中科院分区：
文献类型：
--
作者：
Gardiner-Garden, M;Littlejohn, T G
微阵列技术已成为最重要的功能基因组技术之一。导致微阵列数据库的扩散。探索这项技术的研究人员可能很难知道哪些生物信息学系统最能满足他们的要求。为了更好地了解可用系统，对微阵列数据库进行了调查和比较分析。该调查包括当前可用的数据库，以及应在2001年初可用的数据库。数据库分为三类：（i）可以在本地安装的数据库，（ii）那些可用于公共数据提交和（iii）的数据库。那些可用于公共查询。询问了微阵列基因表达数据库的开发人员有关其数据库的范围和可用性，其系统要求，其未来对MGED（微阵列基因表达数据库）标准的遵守及其相关分析工具的问题。参与者包括Amad（Stanford/Berkeley/UCSF），ArrayExpress（EBI），CHIPDB（MIT/Whitehead），Genex（NCGR）（NCGR），Genet（Silicon Genetics），GenEdirector（Biodiscovery）（Biodiscovery），Geo（NCBI），GXSD（Jackson Laboratory），GEO（NCBI），GXSD（Jackson Laboratory），，杰克逊实验室， MADB（NCI），MaxDSQL（曼彻斯特大学），Nomad（UCSF），Rad（宾夕法尼亚大学）和SMD（斯坦福大学）。联系了其他数据库开发人员，但在手稿准备时没有数据。每个数据库都履行了不同的角色，反映了微阵列用户的广泛不同需求。
Microarray technology has become one of the most important functional genomics technologies. A proliferation of microarray databases has resulted. It can be difficult for researchers exploring this technology to know which bioinformatics systems best meet their requirements. In order to obtain a better understanding of the available systems, a survey and comparative analysis of microarray databases was undertaken. The survey included databases that are currently available, as well as databases that should become available in early 2001. Databases fall into three categories: (i) those that can be installed locally, (ii) those available for public data submission and (iii) those available for public query. Developers of microarray gene-expression databases were asked questions regarding the scope and availability of their database, its system requirements, its future compliance with MGED (Microarray Gene Expression Database) standards, and its associated analytical tools. Participants included AMAD (Stanford/Berkeley/UCSF), ArrayExpress (EBI), ChipDB (MIT/Whitehead), GeneX (NCGR), GeNet (Silicon Genetics), GeneDirector (BioDiscovery), GEO (NCBI), GXD (Jackson Laboratory), mAdb (NCI), maxdSQL (University of Manchester), NOMAD (UCSF), RAD (University of Pennsylvania) and SMD (Stanford University). Other database developers were contacted but data was not available at the time of manuscript preparation. Each database fulfils a different role, reflecting the widely varying needs of microarray users.