Experimental production of sheep pulmonary adenomatosis (Jaagsiekte)

Experimental production of sheep pulmonary adenomatosis (Jaagsiekte)
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绵羊肺腺瘤病(Jaagsiekte)的实验生产

DOI:
10.1038/264183a0
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发表时间:
1976
期刊:
影响因子:
64.8
通讯作者:
M. Norval
M. Norval
中科院分区:
综合性期刊1区
文献类型:
--
作者:
W. B. Martin;F. Scott;J. Sharp;K. Angus;M. Norval

文献摘要

被引文献

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SHEEP pulmonary adenomatosis (SPA) or Jaagsiekte is a contagious disease of unknown aetiology1. A herpesvirus has been isolated from such tumours in Britain2 and in Africa3,4 but attempts to produce adenomata with this virus have been unsuccessful (ref. 5 and W.B.M., G. Robinson, and K.W.A., in preparation). More recently, evidence has been presented that a type C virus with a density on a sucrose gradient of 1.5–1.20 g ml−1, containing 60–70S RNA and RNA-directed DNA polymerase (reverse transcriptase) is present in the adenomatous tissue6. We wish to describe the production of SPA tumours in sheep experimentally infected with both agents.