Lactobacillus GG:: Bacteriology and clinical applications

Lactobacillus GG:: Bacteriology and clinical applications
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DOI:
10.1016/j.gtc.2005.05.011
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发表时间:
2005-09-01
影响因子:
3.7
通讯作者:
Gorbach, SL
Gorbach, SL
中科院分区:
医学3区
文献类型:
--
作者:
Doron, S;Snydman, DR;Gorbach, SL

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鼠李糖乳杆菌 GG (LGG) 已在人类和实验动物中进行了广泛研究,具有多种用途。目前,有强有力的证据表明LGG可用于急性腹泻和抗生素相关性腹泻。数据表明,LGG 可能有助于治疗和预防特应性疾病以及预防日托感染、旅行者腹泻和龋齿。炎症性肠病、艰难梭菌和囊性纤维化的研究结果令人鼓舞。 LGG 预防癌症、类风湿关节炎、肠易激综合征、肝病和糖尿病的研究值得更多研究。
Lactobacillus rhamnosus GG (LGG) has been studied extensively in humans and experimental animals for a wide variety of uses. At present, there is strong evidence that LGG can be used in acute diarrhea and antibiotic-associated diarrhea. Data suggest that LGG may be useful for treatment and prevention of atopic disease and for prevention of infections acquired in daycare, traveler's diarrhea, and dental caries. Results from studies in inflammatory bowel disease, Clostridium difficile, and cystic fibrosis are promising. Studies of LGG for cancer prevention, rheumatoid arthritis, irritable bowel syndrome, liver disease, and diabetes warrant more research.