Marijuana withdrawal among adults seeking treatment for marijuana dependence
Marijuana withdrawal among adults seeking treatment for marijuana dependence
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DOI：
10.1046/j.1360-0443.1999.94913114.x
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发表时间：
1999-09-01
期刊：
影响因子：
6
通讯作者：
Hughes, JR
中科院分区：
文献类型：
--
作者：
Budney, AJ;Novy, PL;Hughes, JR
目标。大麻戒断的临床相关性尚未确定。这项研究首次记录了大麻依赖成年人临床样本中感知到的大麻戒断症状的发生率和严重程度。测量。 54 名因大麻依赖而寻求门诊治疗的患者根据最近的大麻戒断情况填写了包含 22 项的大麻戒断症状清单。发现。大多数人 (57%) 表示他们经历过超过或等于 6 种至少中等严重程度的症状，47% 的人经历过超过或等于 4 种严重程度的症状。具有精神症状和更频繁吸食大麻的人的戒断严重程度更高。结论。这项研究为停止经常使用大麻后出现的一系列戒断症状提供了进一步的支持。报告的情感和行为症状与之前实验室和访谈研究中观察到的一致。由于戒断症状经常是其他滥用药物临床干预的目标，因此这也可能适合大麻。
Aims. The clinical relevance of marijuana withdrawal has not been established. This study is the first to document the incidence and severity of perceived marijuana withdrawal symptoms in a clinical sample of marijuana-dependent adults. Measurements. Fifty-four people seeking outpatient treatment for marijuana dependence completed a 22-item Marijuana Withdrawal Symptom checklist based on their most recent period of marijuana abstinence. Findings. The majority (57%) indicated that they had experienced greater than or equal to six symptoms of at least moderate severity and 47% experienced greater than or equal to four symptoms rated as severe. Withdrawal severity was greater in those with psychiatric symptomatology and more frequent marijuana use. Conclusions. This study provides further support for a cluster of withdrawal symptoms experienced following cessation of regular marijuana use. The affective and behavioral symptoms reported were consistent with those observed in previous laboratory and interview studies. Since withdrawal symptoms are frequently a target for clinical intervention with other substances of abuse, this may also be appropriate for marijuana.