Toxoplasmosis in patients receiving immunosuppressive therapy.
Toxoplasmosis in patients receiving immunosuppressive therapy.
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接受免疫抑制治疗的患者患有弓形体病。
DOI：
10.1001/jama.1970.03170040061017
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发表时间：
1970
期刊：
影响因子：
--
通讯作者：
S. Cohen
中科院分区：
文献类型：
--
作者：
S. Cohen
两名患者发生了致命的播散性弓形虫病，这两名患者均表现出严重的中枢神经系统受累。一名患者，据报道有水痘带状疱疹，接受免疫抑制治疗后，同种肾移植，是第三个已知的患者报告这种感染性并发症。另一例患者因淋巴增生性疾病导致的重度骨髓损伤接受类固醇治疗，病理结果提示潜伏性疾病激活。
Lethal, disseminated toxoplasmosis occurred in two patients, both of whom demonstrated severe central nervous system involvement. One patient, reported to have varicella zoster, was receiving immunosuppressive therapy following renal homotransplantation and is the third known patient to be reported with this infectious complication. The other patient was receiving steroids for severe marrow impairment due to a lymphoproliferative disorder, and had pathologic findings suggesting activation of latent disease.