Gastric Carcinoma with Bone Marrow Metastasis: A Case Series
Gastric Carcinoma with Bone Marrow Metastasis: A Case Series
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DOI：
10.5230/jgc.2014.14.1.54
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发表时间：
2014-03-01
影响因子：
2.5
通讯作者：
Oksuzoglu, Berna
中科院分区：
文献类型：
--
作者：
Ekinci, Ahmet Siyar;Bal, Oznur;Oksuzoglu, Berna
胃癌是癌症相关死亡的主要原因。在诊断时，大多数患者通常有无法切除或转移的疾病。最常见的转移部位是肝脏和腹膜，但在晚期，可能会有转移到身体的任何部位。骨髓是实体瘤的重要转移部位，预后较差。在胃癌病例中，骨髓转移通常发生在较年轻的患者和低分化肿瘤患者中。由于组织形态不良以及全血细胞减少的发生，预后恶化。标准化疗的效果尚不清楚，因为生存时间仅限于几周。本报告旨在评估5例有骨髓转移的胃癌患者，以强调这种情况的重要性。
Gastric cancer is a major cause of cancer-related mortality. At the time of diagnosis, majority of the patients usually have unresectable or metastatic disease. The most common sites of metastases are the liver and the peritoneum, but in the advanced stages, there may be metastases to any region of the body. Bone marrow is an important metastatic site for solid tumors, and the prognosis in such cases is poor. In gastric cancer cases, bone marrow metastasis is usually observed in younger patients and in those with poorly differentiated tumors. Prognosis is worsened owing to the poor histomorphology as well as the occurrence of pancytopenia. The effect of standard chemotherapy is unknown, as survival is limited to a few weeks. This report aimed to evaluate 5 gastric cancer patients with bone marrow metastases to emphasize the importance of this condition.