Decrease in cell free DNA levels following participation in stress reduction techniques among women undergoing infertility treatment
Decrease in cell free DNA levels following participation in stress reduction techniques among women undergoing infertility treatment
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DOI：
10.1007/s00737-013-0407-2
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发表时间：
2014-06-01
影响因子：
4.5
通讯作者：
Har-Vardi, Iris
中科院分区：
文献类型：
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作者：
Czamanski-Cohen, Johanna;Sarid, Orly;Har-Vardi, Iris
这项初步研究检查了14名接受体外受精（IVF）和胚胎移植（ET）治疗的女性在开始IVF治疗前血浆CFD水平高于正常水平的情况下，基于减压技术的实践，血浆游离DNA（CFD）水平的差异。使用Wilcoxon非参数检验来检查每组中时间点之间CFD水平下降速率的显著性。配对样本t检验分别检查了每组中每个参与者的CFD水平变化。我们发现，从事这些技术的女性血浆CFD降低，低于与未练习者相比被认为升高的水平。高血浆CFD水平与IVF失败有关。减压技术可促进导致血浆CFD水平降低的生理变化。
This pilot study examined differences in plasma cell free DNA (CFD) levels based on practice of stress reduction techniques among 14 women undergoing in vitro fertilization (IVF) and embryo transfer (ET) treatment who had higher than normal levels of plasma CFD before beginning IVF treatment. Wilcoxon nonparametric tests were used to examine the significance of the rate of decline in CFD levels between the time points in each of the groups. A paired sample t-test examined the changes in CFD levels among each participant in each of the groups separately. We found that women who engaged in these techniques had reduced plasma CFD, below what is considered elevated in comparison to those who did not practice. High plasma CFD levels have been associated with IVF failure. Stress reduction techniques may facilitate physiological changes that lead to the reduction of plasma CFD levels.