Long-term outcomes after heart failure hospitalization during the COVID-19 pandemic: a multisite report from heart failure referral centers in London.
Long-term outcomes after heart failure hospitalization during the COVID-19 pandemic: a multisite report from heart failure referral centers in London.
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DOI：
10.1002/ehf2.13579
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发表时间：
2021-12
影响因子：
3.8
通讯作者：
McDonagh TA
中科院分区：
文献类型：
--
作者：
Ta Anyu A;Badawy L;Cannata A;Bromage DI;Rind IA;Albarjas M;Piper S;Shah AM;McDonagh TA
在COVID-19大流行的第一波期间，因心力衰竭（HF）住院的患者的住院结局更差。然而，他们的长期结果是未知的。我们描述了在COVID-19大流行期间存活出院的患者与2019年在伦敦两个转诊中心住院的患者的长期结局。研究共纳入了2020年1月7日至6月14日期间在两个南伦敦转诊中心因急性HF住院治疗后存活的512例患者，并与2019年同期的725例患者进行了比较。主要结局为全因死亡率。2020年入院患者的人口统计学特征与2019年队列相似。中位（IQR）随访时间为622（348-691）天。与2019年同期相比，2020年入院患者的出院后全因死亡率仍显著较高（P <0. 01），这可能与观察到的护理地点差异有关，在COVID-19大流行期间，在心脏病专科病房管理的患者较少。在第一波COVID-19大流行期间因HF住院与存活出院患者的全因死亡率较高相关。有必要进一步研究，以确定这些不良结果的预测因素，以改善急性心力衰竭管理关键时期的门诊管理。
Patients hospitalized for heart failure (HF) had worse in‐hospital outcomes during the first wave of the COVID‐19 pandemic. However, their long‐term outcomes are unknown. We describe long‐term outcomes among patients who survived to hospital discharge compared with patients hospitalized in 2019 from two referral centers in London during the COVID‐19 pandemic. In total, 512 patients who survived their hospitalization for acute HF in two South London referral centers between 7 January and 14 June 2020 were included in the study and compared with 725 patients from the corresponding period in 2019. The primary outcome was all‐cause mortality. The demographic characteristics of patients admitted in 2020 were similar to the 2019 cohort. Median (IQR) follow‐up was 622 (348–691) days. All‐cause mortality after discharge remained significantly higher for patients admitted in 2020 compared with the equivalent period in 2019 (P < 0.01), which may relate to observed differences in place of care with fewer patients being managed on specialist cardiology wards during the COVID‐19 pandemic. Hospitalization for HF during the first wave of the COVID‐19 pandemic was associated with higher all‐cause mortality among patients who survived to discharge. Further studies are necessary to identify predictors of these adverse outcomes to improve outpatient management during a critical period in the management of acute HF.
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