Physical activity, physical fitness, and all-cause and cancer mortality: A prospective study of men and women
Physical activity, physical fitness, and all-cause and cancer mortality: A prospective study of men and women
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DOI：
10.1016/s1047-2797(96)00059-2
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发表时间：
1996-09-01
影响因子：
5.6
通讯作者：
Kohl, HW
中科院分区：
文献类型：
--
作者：
Kampert, JB;Blair, SN;Kohl, HW
我们研究了1970年至1989年期间在德克萨斯州达拉斯的库珀诊所检查的7080名女性和25,341名男性队列中身体健康和身体活动与全因死亡率和癌症死亡率的关系。通过最大跑步机运动试验评估基线时的身体健康，同时在服务员健康习惯问卷中自我报告身体活动。男性和女性在基线时的平均年龄约为43岁（范围为20至88岁），平均随访时间为8年。到1989年底，这些妇女提供了52 982人-年的观察，造成89人死亡，其中44人死于癌症。男性贡献了211，996人年，造成601人死亡，其中179人死于癌症。在对年龄、体检年份、吸烟习惯、慢性病和心电图异常等基线差异进行校正后，我们发现男性和女性的全因死亡风险与身体健康水平之间存在强烈的负相关（趋势P < 0.001）。体力活动男性的全因死亡率也低于久坐男性（趋势P < 0.01）。然而，在女性中，自我报告的身体活动与各种原因的死亡风险没有显着相关。随着男性健康水平的提高，癌症死亡风险急剧下降（趋势P < 0.001），而女性的梯度是暗示性的，但不显著（趋势P = 0.07）。体力活动的男性癌症死亡风险也低于久坐的男性（趋势P = 0.002），但女性体力活动与癌症死亡率无关。(C)Elsevier Science Inc.出版。
We studied physical fitness and physical activity in relation to all-cause and cancer mortality in a cohort of 7080 women and 25,341 men examined at the Cooper Clinic in Dallas, Texas, during 1970 to 1989. Physical fitness was assessed at baseline by a maximal treadmill exercise test, while physical activity was self-reported on the attendant health habits questionnaire. Both men and women averaged about 43 years of age at baseline (range, 20 to 88 years), and they were followed for similar to 8 years on average. Through the end of 1989, the women contributed 52,982 person-years of observation and incurred 89 deaths, including 44 deaths due to cancer. The men contributed 211,996 person-years and incurred 601 deaths, with 179 due to cancer. After adjustment for baseline differences in age, examination year, cigarette habit, chronic illnesses, and electrocardiogram abnormalities, we found a strong inverse association between risk of all-cause mortality and level of physical fitness in both men and women (P for trend < 0.001). Physically active men also were at lower risk of all-cause mortality than were sedentary ones (P for trend < 0.01). Among women, however, self-reported physical activity was not significantly related to risk of death from all causes. The risk of mortality from cancer declined sharply across increasing levels of fitness among men (P for trend < 0.001), whereas among women the gradient was suggestive but not significant (P for trend = 0.07). Physically active men also were at lower risk of death from cancer than were sedentary men (P for trend = 0.002), but among women physical activity was unrelated to cancer mortality. (C) 1996 by Elsevier Science Inc.