Spectral integration in the inferior colliculus of the mustached bat
Spectral integration in the inferior colliculus of the mustached bat
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DOI：
10.1523/jneurosci.20-22-08533.2000
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发表时间：
2000-11-15
影响因子：
5.3
通讯作者：
Wenstrup, JJ
中科院分区：
文献类型：
--
作者：
Leroy, SA;Wenstrup, JJ
包括定向和社会交流在内的声学行为依赖于神经对整个声音频谱信息的整合。在许多物种中，光谱整合是由组合敏感神经元执行的，当声音中不同的光谱元素组合时，反应最好。这些通常被认为是听觉前脑信息处理的一个特征。在胡子蝙蝠的下丘（IC），他们是常见的频率表示与声纳信号，但尚未在其他地方报道，在此蝙蝠的IC或IC的其他物种。我们检查了与生物声纳无关的小胡子蝙蝠IC频率表示中组合敏感神经元的存在。记录了75个单单位响应，最佳频率在10-23或32-47 kHz频段。26个在一个波段显示单一的兴奋性调谐曲线，在另一个波段没有额外的第二个信号的反应。剩下的49个对10-23和32-47 kHz频段的声音都有反应，但反应类型各不相同。高频段的声音通常是兴奋性的，而低频段的声音要么促进要么抑制对高频信号的反应。当高频率和低频率刺激同时出现时，相互作用通常最强，但相互作用的强度不同。超过三分之一的神经元形成了一个独特的子集;它们对带通噪声的反应最敏感，并且都是组合敏感的。我们认为，这些组合敏感的相互作用被激活的胡子蝙蝠社会发声的元素。如果是这样的话，在许多物种中，社会发声的神经元整合特征分析发生在IC。
Acoustic behaviors including orientation and social communication depend on neural integration of information across the sound spectrum. In many species, spectral integration is performed by combination-sensitive neurons, responding best when distinct spectral elements in sounds are combined. These are generally considered a feature of information processing in the auditory forebrain. In the mustached bat's inferior colliculus (IC), they are common in frequency representations associated with sonar signals but have not been reported elsewhere in this bat's IC or the IC of other species. We examined the presence of combination-sensitive neurons in frequency representations of the mustached bat's IC not associated with biosonar. Seventy-five single- unit responses were recorded with the best frequencies in 10-23 or 32-47 kHz bands. Twenty-six displayed single excitatory tuning curves in one band with no additional responsiveness to a second signal in another band. The remaining 49 responded to sounds in both 10-23 and 32-47 kHz bands, but response types varied. Sounds in the higher band were usually excitatory, whereas sounds in the lower band either facilitated or inhibited responses to the higher frequency signal. Interactions were usually strongest when the higher and lower frequency stimuli were presented simultaneously, but the strength of interactions varied. Over one-third of the neurons formed a distinct subset; they responded most sensitively to bandpass noise, and all were combination sensitive. We suggest that these combination-sensitive interactions are activated by elements of mustached bat social vocalizations. If so, neuronal integration characterizing analysis of social vocalizations in many species occurs in the IC.