Sensitivity and specificity of body mass index and skinfold thicknesses in detecting excess adiposity in children aged 8-12 years
Sensitivity and specificity of body mass index and skinfold thicknesses in detecting excess adiposity in children aged 8-12 years
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DOI：
10.1080/0301446021000033409
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发表时间：
2003-03-01
影响因子：
1.7
通讯作者：
Battistini, N
中科院分区：
文献类型：
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作者：
Bedogni, G;Iughetti, L;Battistini, N
主要目标：本研究的目的是评估的敏感性（SN）和特异性（SP）的身体质量指数（BMI）和皮褶厚度在检测过度肥胖的children.Research design：横断面材料和方法：986名儿童（500名女性和486名男性）年龄10 +/- 1岁（平均值+/- SD;范围：8-12岁）进行了研究。所有患者均接受人体测量和生物电阻抗分析（BIA）。对52名儿童进行了双能X线吸收测定法（DXA），以开发一种用于评估BIA无脂肪质量（FFM）的人群特异性算法。该算法应用于其余934名儿童，以估计他们的FFM。通过从体重（Wt）中减去FFM获得脂肪质量（FM）。FM：Wt值转换为Z评分并转换为19个百分位数类别（从5到95，步长为5）。对BMI和四种皮褶厚度（三头肌、二头肌、肩胛下和髂上; lt-4SF）的对数转换总和进行相同的程序。过度肥胖定义为FM：Wt水平大于内部推导的第85百分位数。结果：在934例合并样本中，BMI第95百分位数的SN和SP分别为0.39和0.99，BMI第85百分位数的SN和SP分别为0.65和0.95，lt-4SF第85百分位数的SN和SP分别为0.75和0.94。在本研究中使用的BMI量表在检测8-12岁儿童过度肥胖时具有高SP而低SN。使用四个皮褶的总和有可能增加这个年龄段儿童过度肥胖筛查计划的SN。
Primary objective: The study aimed to evaluate the sensitivity (SN) and specificity (SP) of body mass index (BMI) and skinfold thicknesses in detecting excess adiposity in children.Research design: Cross-sectional.Materials and methods: 986 children (500 females and 486 males) aged 10 +/- 1 years (mean +/- SD; range: 8-12 years) were studied. All underwent anthropometric measurements and bioelectrical impedance analysis (BIA). Dual-energy X-ray absorptiometry (DXA) was performed in 52 children to develop a population-specific algorithm for the assessment of fat-free mass (FFM) from BIA. The algorithm was applied to the remaining 934 children to estimate their FFM. Fat mass (FM) was obtained by subtracting FFM from weight (Wt). Values of FM:Wt were transformed in Z-scores and converted into 19 percentile categories (from 5 to 95 in steps of 5). The same procedure was performed with BMI and the log-transformed sum of four skinfold thicknesses (triceps, biceps, subscapular and suprailiac; lt-4SF). Excess adiposity was defined as a level of FM:Wt greater than the internally derived 85th percentile. SN and SP of each internally derived percentile of BMI and lt-4SF in detecting excess adiposity were calculated.Results: In the pooled sample (n = 934), SN and SP were 0.39 and 0.99 for the 95th percentile of BMI, 0.65 and 0.95 for the 85th percentile of BMI, and 0.75 and 0.94 for the 85th percentile of lt-4SF.Conclusions: BMI percentiles employed in the present study have a high SP but a low SN in detecting excess adiposity in 8-12-year-old children. The use of the sum of four skinfolds has the potential to increase the SN of a screening programme for excess adiposity in children of this age.