SOLUTION CONFORMATION OF ALPHA-D(1-3)-LINKED AND ALPHA-D(1-6)-LINKED OLIGOMANNOSIDES USING PROTON NUCLEAR MAGNETIC-RESONANCE
SOLUTION CONFORMATION OF ALPHA-D(1-3)-LINKED AND ALPHA-D(1-6)-LINKED OLIGOMANNOSIDES USING PROTON NUCLEAR MAGNETIC-RESONANCE
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DOI：
10.1021/bi00275a007
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发表时间：
1983-01-01
期刊：
影响因子：
2.9
通讯作者：
CARVER, JP
中科院分区：
文献类型：
--
作者：
BRISSON, JR;CARVER, JP
The solution conformations of synthetic methyl mannobiosides and a methyl mannotrioside containing .alpha.D(1-3) and .alpha.D(1-6) linkages were determined by 1H NMR techniques, namely, the nuclear Overhauser effect and 1H relaxation time measurements. 3J(C,H) coupling constants, obtained from a compound enriched with 13C, were also used. The allowed conformations were in agreement with those determined from potential energy calculations and crystal structures. The methyl mannotrioside is an analog of a mannotriose unit which occurs naturally in the core of asparagine-linked glycopeptides and in an arm of high mannose N-linked glycopeptides.
