Molecular Pathology of Human Haemoglobin
Molecular Pathology of Human Haemoglobin
复制标题
人类血红蛋白的分子病理学
作者:
M. Perutz;H. Lehmann
The haemoglobin molecule is insensitive to replacements of most amino-acid residues on its surface, but extremely sensitive to even quite small alterations of internal non-polar contacts, especially those near the haems. Replacements at the contacts between α and β-subunits affect respiratory function.