Chemical Interactions between Organisms in Microbial Communities
Chemical Interactions between Organisms in Microbial Communities
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DOI：
10.1159/000219369
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发表时间：
2009-01-01
期刊：
影响因子：
--
通讯作者：
Surette, Michael G.
中科院分区：
文献类型：
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作者：
Duan, Kangmin;Sibley, Christopher D.;Surette, Michael G.
细菌几乎只与其他微生物生活在一起，并且通常与多细胞宿主相关联。这些社区能够随着时间的推移保持复杂的结构和功能的稳定性，并表现出迷人的弹性特性，以应对环境变化。这是微生物与环境以及社区成员之间相互作用的结果。在微生物群落中发生大量的化学相互作用，其中初级和次级代谢产物有助于生物体之间的大量相互作用。这些化学物质包括各种营养物质、有毒或中性代谢副产物、抗生素和细胞间信号分子。这些化学和物理信号促进了微生物之间的关系，这种关系可以是竞争性的、合作性的或中性的，因此负责决定群落结构。反过来，周围的社区改变了个体细胞的微环境，这些细胞以组合的方式对化学和环境线索做出反应。目前实验室对微生物之间相互作用的遗传学和机制的理解有能力帮助我们了解复杂的微生物群落在自然环境中的行为。在这一章中，我们回顾了目前对微生物通讯的理解，从遗传和分子方面，我们目前对它们的生态作用的理解。版权所有（C）2009 S. Karger AG，巴塞尔
Bacteria live almost exclusively in communities with other microorganisms, and often in association with multicellular hosts. These communities are capable of maintaining complex structural and functional stability over time, and exhibit fascinating properties of resiliency in response to environmental changes. This is a result of interactions between microbes and the environment and amongst members of the community. A multitude of chemical interactions occur in microbial communities where primary and secondary metabolites contribute to a wealth of interactions between organisms. The chemicals include a variety of nutrients, toxic or neutral metabolic byproducts, antibiotics, and cell-cell signaling molecules. These chemical and physical signals facilitate microbial relationship that can be competitive, cooperative or neutral, and thus are responsible for determining community structure. In turn, the surrounding community changes the microenvironment of individual cells who respond to chemical and environmental cues in a combinatorial manner. Current laboratory understanding of the genetics and mechanisms of interactions between microbes has the power to help us understand how complex microbial communities behave in the natural environment. In this chapter we review the current understanding of microbial communication, from the genetic and molecular aspects, to our current understanding of their ecological role. Copyright (C) 2009 S. Karger AG, Basel