The role of fundamental research and biotechnology in finding solutions to the global problem of antibiotic resistance.
The role of fundamental research and biotechnology in finding solutions to the global problem of antibiotic resistance.
复制标题
基础研究和生物技术在寻找全球抗生素耐药性问题解决方案中的作用。
DOI:
10.1093/clinids/24.supplement_1.s148
复制
发表时间:
1997
影响因子:
11.8
通讯作者:
R. Hancock
中科院分区:
文献类型:
--
作者:
R. Hancock
Resistance to antibiotics is becoming a major problem worldwide. Exacerbating this situation is the fact that few new antibiotics are in the development pipeline, and, indeed, no novel class of antibiotics has been introduced into medical practice in more than 20 years. It is proposed that the solutions to the problem of antibiotic resistance will be found only through fundamental research that will probably use biotechnology as a tool. A variety of novel approaches being utilized in university laboratories and biotechnology companies are outlined. Two approaches in particular, namely, Synsorbs and recombinant cationic peptide antimicrobials, that have been developed through the Canadian Bacterial Diseases Network, a national research consortium, are discussed.