The Steady Polarity Potential of the Human Eye.
The Steady Polarity Potential of the Human Eye.
复制标题
人眼的稳定极性电位。
DOI：
10.1073/pnas.25.1.25
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发表时间：
1939
影响因子：
11.1
通讯作者：
W. R. Miles
中科院分区：
文献类型：
--
作者：
W. R. Miles
在（刚切除的）青蛙眼球中存在电位已经被确认。一些时间。眼部准备的角膜部分电阳性，视网膜区域电阴性。当与这两个区域接触的电极连接到灵敏的振镜时，就会显示出相对稳定的“静止电流”，有时高达10毫伏。除了这个稳定的电位外，在光的刺激下还会产生一个短暂的小“视网膜动作电流”。除青蛙外，对许多其他物种的眼睛进行了研究，得出了类似的结果。“因为从温血动物身上切除的器官很快就会失去活性，所以人们进行了各种尝试，并采用了外科技术，使对哺乳动物眼睛的原位研究成为可能。”以前，科学的兴趣主要集中在眼睛对光的光电反应现象上，因此，虽然对作用电流进行了大量研究，但相对而言，静止电流的现象却被忽视了。一些有价值的早期和最近的尝试利用人眼的潜力研究眼球震颤和其他类型的眼球运动已经完成。从这些可以收集到关于稳定电位本身的零碎信息。本文介绍了一种直接研究人眼原位稳态电位的方法，并报道了一些结果和结论。简要考虑以下主题和材料：
The existence of an electrical potential in the (freshly excised) eyeball of the frog has been recognized for. some time. The corneal portion of the eye preparation is electrically positive, the retinal area negative. A relatively steady" current of rest," sometimes registering as high as 10 milli-volts, is revealed when electrodes placed in contact with these two regions are connected to a sensitive galvanometer. In addition to this steady potential there occurs under the stimulation of light a small transitory" retinal action current." Excised eyes of many other species besides the frog have been studied with similar results.'Because excised preparations from warm-blooded animals soon become inactive, various attempts have been made and surgical techniques employed to make possible potential studies of mammalian eyes in situ.Scientific interest has previously for the most part centered in the phenomenon of the eye's photo-electric response to light, and so while the action currents have been much studied, the phenomenon of the current of rest has been relatively neglected. Some valuable early and recent'attempts to utilize the potential ofthe human eye in studies of nystagmus and other types of eye movement have been made. From these may be gleaned fragmentary information aboutthe steady potential itself. In the present paper a method is described for the direct study of the steady potential in the human eye in situ and some results and conclusions are reported. The following topics and materials are briefly considered: