Work at inpatient care units is associated with an increased risk of SARS-CoV-2 infection; a cross-sectional study of 8679 healthcare workers in Sweden.
Work at inpatient care units is associated with an increased risk of SARS-CoV-2 infection; a cross-sectional study of 8679 healthcare workers in Sweden.
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DOI：
10.1080/03009734.2020.1793039
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发表时间：
2020-11
影响因子：
3.4
通讯作者：
Westman G
中科院分区：
文献类型：
--
作者：
Lidström AK;Sund F;Albinsson B;Lindbäck J;Westman G
在新冠肺炎大流行期间，对医护人员的保护一直是世界各地关注的焦点，但个人防护装备的可用性和质量有时和在某些情况下并不理想。斯德哥尔摩北部乌普萨拉县共有8679名医护人员和医疗支持人员参与了这项横断面研究。对所有受试者进行了抗SARS-CoV-2免疫球蛋白分析，并用Logistic回归模型分析了阳性血清抗体的预测因素，包括人口统计学参数和自我报告的就业特征。总体而言，577人(6.6%)被归类为血清阳性，医护人员和支持人员之间没有统计上的显著差异。在医护人员中，年龄(每年OR 0.987，95%CI 0.980-0.995)、采样时间(OR 1.019/天，95%CI 1.004-1.035)和在门诊工作(OR 0.620，95%CI 0.487-0.788)与感染风险显著相关。与其他具有类似特征和员工人口统计的单位相比，新冠肺炎特定单位的风险并不特别大。我们的发现表明SARS-CoV-2的传播与住院医疗工作有关，并说明在所有住院护理环境中都需要高标准的基本卫生程序。
During the Covid-19 pandemic, the protection of healthcare workers has been in focus throughout the world, but the availability and quality of personal protective equipment has at times and in some settings been suboptimal. A total of 8679 healthcare workers and healthcare support staff in the county of Uppsala, north of Stockholm, were included in this cross-sectional study. All subjects were analysed for IgG anti-SARS-CoV-2, and predictors for positive serostatus were analysed in a logistic regression model including demographic parameters and self-reported employment characteristics. Overall, 577 (6.6%) were classified as seropositive, with no statistically significant differences between healthcare workers and support staff. Among healthcare workers, age (OR 0.987 per year, 95% CI 0.980–0.995), time to sampling (OR 1.019 per day, 95% CI 1.004–1.035), and employment at an outpatient care unit (OR 0.620, 95% CI 0.487–0.788) were statistically significantly associated with risk of infection. Covid-19 specific units were not at particular risk, compared to other units with comparable characteristics and staff demography. Our findings indicate that SARS-CoV-2 transmission is related to inpatient healthcare work, and illustrate the need for a high standard of basic hygiene routines in all inpatient care settings.
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影响因子：
8.8
作者：
Korth, Johannes;Wilde, Benjamin;Herrmann, Anke
通讯作者：
Herrmann, Anke
影响因子：
82.9
作者：
Long, Quan-Xin;Tang, Xiao-Jun;Huang, Ai-Long
通讯作者：
Huang, Ai-Long
影响因子：
9.4
作者：
Bryan, Andrew;Pepper, Gregory;Greninger, Alexander L.
通讯作者：
Greninger, Alexander L.
影响因子：
64.5
作者：
Grifoni, Alba;Weiskopf, Daniela;Sette, Alessandro
通讯作者：
Sette, Alessandro