Temporomandibular joint dysfunction and systemic joint laxity.
Temporomandibular joint dysfunction and systemic joint laxity.
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颞下颌关节功能障碍和全身关节松弛。
DOI：
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发表时间：
1992
期刊：
影响因子：
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通讯作者：
L. Westling
中科院分区：
文献类型：
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作者：
L. Westling
本论文旨在探讨颞下颌关节（TMJ）功能障碍患者的遗传性全身性关节松弛。在TMJ患者和非患者组中，分析了系统性关节松弛对TMJ功能障碍的重要性，并与其他可能的病因（如磨牙和颌骨创伤）进行了比较。研究了颞下颌关节活动度高的患者和正常人的胶原分布和二尖瓣功能。对360名参与者的一般关节活动度进行了评估。74例女性颅下颌功能障碍（CMD）患者与73例同性别、同年龄的对照组比较，患者组出现较多的运动异常个体。颞下颌关节功能障碍患者的关节活动过度明显多于CMD患者诊所的其他患者。多元逐步回归分析表明，活动能力过强是颞下颌关节功能障碍的重要因素。只有在非运动过度的患者中，头部和下颌的创伤与TMJ功能障碍有显著相关。TMJ患者比其他CMD患者或对照组有更多的肌肉骨骼疾病。一项包括200名青少年的非患者调查显示，女性比男性更容易动。在10例颞下颌关节过度活动患者和10例正常对照的超声心动图调查中，与对照组相比，颞下颌关节过度活动患者的另一个全身性倾向的指征是二尖瓣功能更不足。皮肤活检显示，TMJ患者的总胶原值较低，III型胶原与III + I型胶原的比例高于正常对照组。
The purpose of this thesis was to study an inherited disposition, systemic joint laxity, in patients with temporomandibular joint (TMJ) dysfunction. The importance of systemic joint laxity for TMJ dysfunction compared with other supposed etiological factors, such as bruxism and jaw trauma, was analysed in TMJ patients and in non-patient groups. Collagen distribution and mitral valve function were investigated in hypermobile TMJ patients and normal controls. General joint mobility was assessed in 360 participants. Comparing 74 female craniomandibular dysfunction (CMD) patients with 73 controls of the same sex and age, more hypermobile individuals were found in the patient group. Patients with TMJ dysfunction had significantly more hypermobile joints than other patients at a clinic for CMD patients. A multiple stepwise regression analysis established that hypermobility was a more important factor than bruxing for TMJ dysfunction. Trauma to the head and jaw was significantly correlated to TMJ dysfunction only in non-hypermobile patients. TMJ patients had significantly more musculoskeletal complaints than other CMD patients or controls. A non-patient investigation comprising about 200 adolescents showed the females to be significantly more hypermobile than the males. Another indication of a systemic disposition in hypermobile TMJ patients compared with controls was more insufficient mitral valve function in an echocardiographic investigation of 10 hypermobile TMJ patients and 10 normal controls. Skin biopsy revealed lower values of total collagen and a higher ratio of collagen type III to III + I in TMJ patients than in normal controls.