Biological and analytical variation of the human sweating response: implications for study design and analysis
Biological and analytical variation of the human sweating response: implications for study design and analysis
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DOI：
10.1152/ajpregu.00456.2011
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发表时间：
2012-01-01
影响因子：
2.8
通讯作者：
Sawka, Michael N.
中科院分区：
文献类型：
--
作者：
Kenefick, Robert W.;Cheuvront, Samuel N.;Sawka, Michael N.
Kenefick RW, Cheuvront SN, Elliott LD, Ely BR, Sawka MN. Biological and analytical variation of the human sweating response: implications for study design and analysis. Am J Physiol Regul Integr Comp Physiol 302: R252-R258, 2012. First published November 9, 2011; doi:10.1152/ajpregu.00456.2011.-Appropriate quantification of analytical and biological variation of thermoregulatory sweating has important practical utility for research design and statistical analysis. We sought to examine contributors to variability in local forearm sweating rate (SR) and sweating onset (SO) and to evaluate the potential for using bilateral measurements. Two women and eight men (26 +/- 9 yr; 79 +/- 12 kg) completed 5 days of heat acclimation and walked (1.8 l/min (V) over dotO(2)) on three occasions for 30 min in 40 degrees C, 20% RH, while local SR and SO were measured. Local SR measures among days were not different (2.14 +/- 0.72 vs. 2.02 +/- 0.79 vs. 2.31 +/- 0.72 mg.cm(2).min(-1), P = 0.19) nor was SO (10.47 +/- 2.54 vs. 10.04 +/- 2.97 vs. 9.87 +/- 3.44 min P = 0.82). Bilateral SR (2.14 +/- 0.72 vs. 2.16 +/- 0.71 mg.cm(2).min(-1), P = 0.56) and SO (10.47 +/- 2.54 vs. 10.83 +/- 2.48 min, P = 0.09) were similar and differences were
