Does surgery modify growth kinetics of breast cancer micrometastases?
Does surgery modify growth kinetics of breast cancer micrometastases?
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DOI：
10.1054/bjoc.2001.1969
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发表时间：
2001-08-17
影响因子：
8.8
通讯作者：
Bonadonna, G
中科院分区：
文献类型：
--
作者：
Demicheli, R;Valagussa, P;Bonadonna, G
手术应被视为实验动物转移发展的主要干扰因素。1173例接受乳房切除术的患者与250例未经治疗的患者相比，死亡率的不同时间分布表明，原发性肿瘤切除可能导致转移过程的变化，即使是乳腺癌。© 2001年癌症研究运动http://www.bjcancer.com
Surgery should be considered as a major perturbing factor for metastasis development in laboratory animals. The different time distribution of mortality for 1173 patients undergoing mastectomy in comparison with 250 untreated patients suggests that primary tumour removal could result in changes of the metastatic process even for breast cancer. © 2001 Cancer Research Campaign http://www.bjcancer.com