Bone marrow-derived mesenchymal stem cells prevent alopecia areata development through the inhibition of NKG2D expression: A pilot study
Bone marrow-derived mesenchymal stem cells prevent alopecia areata development through the inhibition of NKG2D expression: A pilot study
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DOI：
10.1111/exd.13255
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发表时间：
2017-06-01
影响因子：
3.6
通讯作者：
Choi, Gwang Seong
中科院分区：
文献类型：
--
作者：
Byun, Ji Won;Kim, Hyo Jin;Choi, Gwang Seong
本文讨论了一项研究，重点是使用骨髓间充质干细胞（MSCs），以防止斑秃的发展，通过抑制自然杀伤G2D（NKG2D）细胞的表达。讨论的主题包括间充质干细胞对免疫细胞的免疫调节和抗炎作用，观察研究中的小鼠脱发，以及组织学分析中显示的炎症细胞对真皮的浸润。
The article discusses a study focusing on the use of bone marrow-derived mesenchymal stem cells (MSCs) to prevent alopecia areata development by inhibiting natural killer G2D (NKG2D) cell's expression. Topics discussed include the immunomodulatory and anti-inflammatory effects of MSCs on immune cells, the observance of hair loss in the mice under study, and the infiltration of the dermis by inflammatory cells, as revealed in a histological analysis.