Test-retest reproducibility of 50 kHz linear-electrical impedance myography
Test-retest reproducibility of 50 kHz linear-electrical impedance myography
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DOI：
10.1016/j.clinph.2005.12.029
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发表时间：
2006-06-01
影响因子：
4.7
通讯作者：
Aaron, R
中科院分区：
文献类型：
--
作者：
Rutkove, SB;Lee, KS;Aaron, R
目的：电阻抗肌电描记术（EIM）是一种用于评估肌肉的方法，其中将高频、低强度交流电施加到身体区域，并测量感兴趣肌肉上的所得表面电压图案。在这项研究中，最简单的这些技术，50 kHz的线性EIM的再现性进行了评估，为三个muscles.Methods：50千赫线性EIM进行二头肌，股四头肌，胫骨前肌的30名正常受试者的年龄范围从21岁到90岁，和主要的结果变量，空间平均相位（θ（平均）），测量。在250天内重复测量，两个数据集之间的比较made.Results：繁殖，作为测量的组内相关系数为所有三块肌肉，是非常高的0.970，0.971，和0.938二头肌，股四头肌，胫骨前肌，分别。所有肌肉组合的测量值之间的变异性平均为4.2%，上限为16.8%。结论：50千赫线性EIM显示出出色的重测重现性。这些结果支持了50 kHz线性EIM有可能用作评估疾病状态的简单、快速和非侵入性测量的观点，或者作为个体患者护理的一部分，或者作为临床试验工作中的替代结果测量。(c)2006年国际临床神经生理学联合会。由Elsevier爱尔兰有限公司出版。保留所有权利。
Objective: Electrical impedance myography (EIM) is a method for evaluating muscle in which high-frequency, low-intensity alternating current is applied to a body region and the resulting surface voltage pattern over a muscle of interest is measured. In this study, the reproducibility for the simplest of these techniques, 50 kHz linear-EIM, was assessed for three muscles.Methods: Fifty kilohertz linear-EIM was performed on the biceps, quadriceps, and tibialis anterior of 30 normal subjects ranging in age from 21 to 90 years, and the major outcome variable, the spatially averaged phase (theta(avg)), measured. The measurements were repeated within 250 days and comparisons between the two data sets made.Results: Reproducibility, as measured by the intraclass correlation coefficients for all three muscles, was very high at 0.970, 0.971, and 0.938 for biceps, quadriceps, and tibialis anterior, respectively. Variability between measurements was on average 4.2% for all muscle combined, with an upper limit of 16.8%.Conclusions: Fifty kilohertz linear-EIM demonstrates excellent test-retest reproducibility.Significance: These results support the view that 50 kHz linear-EIM has the potential to be used as a simple, fast, and non-invasive measurement for the assessment of disease status, either as part of individual patient care or as a surrogate outcome measure in clinical trials work. (c) 2006 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.