Cancer survival in England and Wales at the end of the 20th century.
Cancer survival in England and Wales at the end of the 20th century.
复制标题
20 世纪末英格兰和威尔士的癌症生存率。
DOI：
10.1038/sj.bjc.6604571
复制
发表时间：
2008-09-23
影响因子：
8.8
通讯作者：
Coleman, M. P.
中科院分区：
文献类型：
--
作者：
Rachet, B.;Woods, L. M.;Mitry, E.;Riga, M.;Cooper, N.;Quinn, M. J.;Steward, J.;Brenner, H.;Esteve, J.;Sullivan, R.;Coleman, M. P.
自20世纪70年代以来，英格兰和威尔士成年人中大多数癌症的生存率稳步上升，但生活在富裕地区和贫困地区的人之间存在持续的不平等。这些差异在儿童身上是看不到的。对于许多常见的成人癌症，这些生存不平等（“剥夺差距”）在20世纪90年代变得更加明显。本卷介绍了1986-1999年14年间诊断并随访至2001年的成人生存率的扩展分析，包括英格兰和威尔士总体生存率的趋势以及生存率中的剥夺差距的趋势。这些分析包括220万癌症患者的个体肿瘤数据。本文概述了补充的结构-成人中20种最常见的癌症中的每一种的文章，然后是专门研究该器官或系统恶性肿瘤的英国领先临床医生之一的专家评论。现有的数据，质量控制和分析方法在这里描述，而不是重复在每20篇文章。我们开启了临床医生和流行病学家之间关于如何解释观察到的癌症生存趋势和不平等的讨论，我们强调了这些非常不同的观点中一些最重要的对比。直到世纪末，英格兰和威尔士的成年癌症患者的生存率大大提高。尽管生存方面的社会经济不平等现象持续存在，但总体模式表明，这些不平等现象在很大程度上是可以避免的。
Survival has risen steadily since the 1970s for most cancers in adults in England and Wales, but persistent inequalities exist between those living in affluent and deprived areas. These differences are not seen for children. For many of the common adult cancers, these inequalities in survival (the ‘deprivation gap’) became more marked in the 1990s. This volume presents extended analyses of survival for adults diagnosed during the 14 years 1986–1999 and followed up to 2001, including trends in overall survival in England and Wales and trends in the deprivation gap in survival. The analyses include individual tumour data for 2.2 million cancer patients. This article outlines the structure of the supplement – an article for each of the 20 most common cancers in adults, followed by an expert commentary from one of the leading UK clinicians specialising in malignancies of that organ or system. The available data, quality control and methods of analysis are described here, rather than repeated in each of the 20 articles. We open the discussion between clinicians and epidemiologists on how to interpret the observed trends and inequalities in cancer survival, and we highlight some of the most important contrasts in these very different points of view. Survival improved substantially for adult cancer patients in England and Wales up to the end of the 20th century. Although socioeconomic inequalities in survival are remarkably persistent, the overall patterns suggest that these inequalities are largely avoidable.
登录
查看更多内容
影响因子：
8.4
作者：
Brenner, H;Rachet, B
通讯作者：
Rachet, B
影响因子：
6.3
作者：
Carstairs, V
通讯作者：
Carstairs, V
影响因子：
6.3
作者：
Dickman, PW;Auvinen, A;Hakulinen, T
通讯作者：
Hakulinen, T
影响因子：
2
作者：
ESTEVE, J;BENHAMOU, E;RAYMOND, L
通讯作者：
RAYMOND, L
影响因子：
3.4
作者：
Ash, D;Barrett, A;Squire, C
通讯作者：
Squire, C