Avoiding Clinical Misinterpretation and Artifacts of Optical Coherence Tomography Analysis of the Optic Nerve, Retinal Nerve Fiber Layer, and Ganglion Cell Layer.
Avoiding Clinical Misinterpretation and Artifacts of Optical Coherence Tomography Analysis of the Optic Nerve, Retinal Nerve Fiber Layer, and Ganglion Cell Layer.
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DOI：
10.1097/wno.0000000000000422
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发表时间：
2016-12
期刊：
影响因子：
--
通讯作者：
Kardon RH
中科院分区：
文献类型：
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作者：
Chen JJ;Kardon RH
光学相干断层扫描(OCT)已成为诊断视神经疾病的重要工具。随着技术的进一步进步，OCT的结构细节和重复性不断提高。然而，OCT的伪影和误解如果没有被发现，可能会导致疾病的临床误诊。PubMed结合临床和研究经验的文献综述。我们描述了OCT在视神经和神经节细胞分析中看到的最常见的伪影和解释错误。我们提供了这些构件的示例，讨论了其原因，并提供了检测它们的方法。此外，我们讨论了一种系统的OCT分析方法，以促进伪影的识别和避免临床误解。虽然OCT在诊断视神经疾病方面是非常有价值的，但我们需要认识到OCT可能出现的伪影。未能识别其中一些人工制品可能会导致误诊和不适当的调查。
Optical coherence tomography (OCT) has become an important tool for diagnosing optic nerve disease. The structural details and reproducibility of OCT continues to improve with further advances in technology. However, artifacts and misinterpretation of OCT can lead to clinical misdiagnosis of diseases if they go unrecognized. A literature review using PubMed combined with clinical and research experience. We describe the most common artifacts and errors in interpretation seen on OCT in both optic nerve and ganglion cell analyses. We provide examples of the artifacts, discuss the causes, and provide methods of detecting them. In addition, we discuss a systematic approach to OCT analysis to facilitate the recognition of artifacts and to avoid clinical misinterpretation. While OCT is invaluable in diagnosing optic nerve disease, we need to be cognizant of the artifacts that can occur with OCT. Failure to recognize some of these artifacts can lead to misdiagnoses and inappropriate investigations.